Search results for " bmp"
showing 4 items of 4 documents
Targeting chemoresistant colorectal cancer via systemic administration of a BMP7 variant
2020
Abstract Despite intense research and clinical efforts, patients affected by advanced colorectal cancer (CRC) have still a poor prognosis. The discovery of colorectal (CR) cancer stem cell (CSC) as the cell compartment responsible for tumor initiation and propagation may provide new opportunities for the development of new therapeutic strategies. Given the reduced sensitivity of CR-CSCs to chemotherapy and the ability of bone morphogenetic proteins (BMP) to promote colonic stem cell differentiation, we aimed to investigate whether an enhanced variant of BMP7 (BMP7v) could sensitize to chemotherapy-resistant CRC cells and tumors. Thirty-five primary human cultures enriched in CR-CSCs, includ…
Biomethane Production from Anaerobic Co-Digestion of Selected Organic Fraction of Municipal Solid Waste (OFMSW) with Sewage Sludge: Effect of the Ino…
2021
The aim of this study was to evaluate the effect of the inoculum to substrate ratio (ISR) and the mixture ratio between organic fraction of municipal solid waste (OFMSW) and sewage sludge (SS) on the methane production potential achievable from anaerobic co-digestion (AcoD). Biochemical Methane Potential (BMP) assays at mesophilic temperature were used to determine the best AcoD configuration for maximizing methane yield and production rate, as well as to address possible synergistic effects. The maximum methane yield was observed at ISR of 1 and 60% OFMSW: 40% SS as co-digestion mixture, whereas the highest methane production rate was achieved at ISR of 2 with the same mixture ratio (207 m…
Capitolo 12 - Interventi per il trattamento delle acque di pioggia
2014
Efficienza idrologico-idraulica di pavimentazioni semi-permeabili per il controllo degli allagamenti pluviali
2021
La sostenibilità del binomio “acqua – città” è uno spunto interessante di discussione e confronto nell’ambito delle diverse discipline che affrontano il tema dell’ambiente urbano, delle sue continue trasformazioni, e della necessità di resilienza agli allagamenti. Le soluzioni tecniche e tecnologiche oggi a disposizione di chi si occupa di queste problematiche, per affrontare il tema di un rapporto sostenibile tra l’acqua e l’ambiente urbano sono molteplici, alcune tradizionali e di consolidata esperienza, altre innovative e di più recente applicazione sul campo. L’urbanizzazione influisce negativamente sulla formazione e propagazione dei deflussi; nelle aree urbanizzate i rapidi processi d…